Which is Better? Ashwagandha vs St John’s Wort

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During the COVID pandemic, concerns relating to people’s mental and emotional health increased worldwide. According to research carried out by the ADAA (Anxiety and Depression Association of America), around 40 million adults in America get diagnosed with anxiety-related disorders every year. 

Even if you have never suffered from any condition relating to anxiety or depression, there will have been times when you have felt stressed or worried about something. This is all part of who we are. 

However, there are certain things you can do to help alleviate stress in your life. Exercise, yoga, and massage therapy are proven effective at helping to reduce stress levels. Also, there are specific natural herbal remedies and dietary supplements you can use as well. 

Below we look closely at two such herbal supplements that can help to reduce stress levels. The two we are looking at are Ashwagandha and St John’s Wort. 

Which of these is the best of all the herbal supplements you can take to reduce stress levels? We will answer this question and more.

Which is Better For Helping to Alleviate Anxiety?

Anyone who suffers from anxiety will sometimes think about using natural remedies instead of prescription antidepressants. This is because they feel that some antidepressant medications, such as benzodiazepine or beta-blockers, lead to them suffering from unwanted side effects. 

However, before any patients with anxiety disorders decide to use natural popular supplements instead of or along with prescribed medications, they should discuss the matter with their doctor first. Certain herbs can cause specific side effects or may not be compatible with the patient’s medication. 


Also called Withania Sominfera, this particular herb has been used for a long time to help treat anxiety disorders. It has been shown to have anti-stress and antioxidants as well as anti-inflammatory properties. 

In 2014, clinical studies were carried out on five people, and it helped to show what effect using Ashwagandha had on these people suffering from symptoms of depression and anxiety. Out of the five people who took part in the study, clinical evidence was found that four began to suffer a lot less from anxiety. 

What Are the Benefits of Taking Ashwagandha?

There are several benefits to be gained by anyone looking for an alternative treatment for depression or generalized anxiety disorder when considering taking this flowering plant in supplement form. These benefits include:

1. Reduces Stress Levels 

This herb’s antioxidant properties can help reduce your stress levels by as much as 80%. It also contains specific properties that can reduce the amount of stress-related hormones your body produces by up to 26%. 

2. Reduces Anxiety 

If your stress levels get reduced, so do your anxiety levels. If you find yourself constantly under pressure, including this supplement in your diet would help combat your increased stress levels by helping to improve brain health. 

3. Helps Fight Depression 

We have all realized that depression is a severe mental health condition. Most people tend to think that the best remedy for depression is to take antidepressant drugs prescribed for them by their healthcare provider. However, they are wrong. It is perfectly safe for people with depression to take Ashwagandha alongside prescription drugs as it causes no side effects. 

How to Use Ashwagandha

Most experts suggest that a daily dose of 300mg of this medicinal herb is safe. You can either take Ashwagandha root in capsule or tablet form, but you may find taking it as a liquid extract more effective.

If you consider using these herbal products in place of or alongside over-the-counter drugs or prescription medications, you should speak to your doctor first. 

St John’s Wort 

This herb has been favored by many who use any kind of alternative medicine to treat various medical conditions such as depressive disorder or mixed anxiety disorders. This traditional herb, also known as Hypericum Perforatum, has been used as an alternative remedy for mood and mental illnesses for many years now. 

 Ashwagandha vs St John's Wort

It has been proven effective as a treatment for anxiety and is traditionally used as a natural alternative remedy for depression. 

Although a few unreplicated trials have been carried out on people using a St John’s Wort supplement, clinical trials on rats in 2018 showed how effective it could be in treating anxiety. 

It is widely believed that these kinds of herbal medicines help boost mood and provide some relief from the symptoms of depression. However, there is still little clear evidence of effectiveness of how it works concerning treatment for anxiety disorders. It may be because there are specific properties within medicinal plants like these that have an effect on the brain. 

Those who are carrying out research to garner clinical evidence into this plant believe that certain ingredients in it cause levels of certain chemicals in the brain to increase. They suspect that hyperforin and hypericin, both found in St John’s Wort, lead to the production of serotonin in the brain. 

What Are the Benefits of Taking St John’s Wort for Depression?

1. Has Great Anti-Depressant Qualities 

As already discussed, it is used widely to help relieve the symptoms of mild to moderate depression. This is because it is a combination of antidepressant chemicals that delay or prevent the uptake of certain neurotransmitters in the brain, such as norepinephrine, dopamine, and serotonin. 

2. Helps to Relieve Anxiety-Related Disorders

St John’s Wort extract isn’t only effective in helping people combat the symptoms associated with depression. It is also a nutritional supplement that can help people suffering from anxiety or panic attacks. It does this by helping to regulate hormones in the body. It also contains specific properties that help bring your metabolism and internal clock back in sync. 

3. Helps to Reduce Mood Swings 

This alternative medicine is regularly recommended for women suffering from premenstrual syndrome or those going through menopause. Again, as mentioned above, it contains specific properties that help regulate the production of hormones in the body. 

How to Use St John’s Wort 

Natural medicines made up of St John’s Wort extracts are safe to use in doses of between 600 and 1,800mg for each serving. To help relieve any generalized anxiety disorder symptoms, the experts claim, based upon scientific evidence, that you begin by taking the lowest dosage possible.

So you should begin with just taking 600mg each day to provide you with the positive effects you desire. Before you do, remember to discuss whether you can take such natural medicines with your prescription antidepressants first. This ensures that they will not result in you suffering any adverse events. 

Ashwagandha vs St John’s Wort: Why Take a Combination of These Natural Treatments 

Below we take a closer look at why taking a combination of these two popular herbs to treat depression and anxiety disorders may be a good idea.

Important Things to Remember 

So before you even consider taking either Ashwagandha or St John’s Wort or both, please discuss them with your doctor first. 

The biggest mistake you could make is taking these types of supplements for depression on their own. You must use a combination of these herbal products to help when you suffer from anxiety, depression, or both. 

Be careful, though. You don’t want to end up overdoing it. 

It is crucial to find a supplement that combines St John’s Wort extracts and Ashwagandha so that you are taking these supplements in safe doses. 

Safety Tips For Using Natural Medicines 

You need to be careful when you plan to use such natural medicines to help treat depression, anxiety, or other medical conditions.

The following tips will help ensure that you use these natural medicines to avoid dealing with any adverse effects. 

1. Make Sure You Follow the Instructions

Never exceed the dosage that has been recommended or take it for any longer than your healthcare provider recommends. 

2. Keep a Log of What You Take 

Take a note of what you are taking, how much, and for how long. Also, make a note of any positive or adverse effects they have on you. You should discontinue using any of these natural supplements if they aren’t proving effective or aren’t helping you to achieve your goals. 

Which is Better Ashwagandha vs St John's Wort

3. Be Careful About Which Brand You Use

When choosing which of these natural medicines you want, you should select the brands where independent sources have carried out tests on them. Many companies such as US Pharmacopeia and NSF International perform such tests to ensure that they can do what the manufacturer claims. 

Let’s Wrap Things Up 

As you will soon discover, plenty of natural medicines are made up of various popular herbs that can help treat disorders like Bipolar disorder, manic depression, anxiety, postpartum depression, and even panic attacks.

So, Ashwagandha vs St John’s Wort: which is better? The answer is neither as both are very beneficial. Patients with anxiety disorders can benefit from taking natural medicines as long as they stick to taking the correct dosage. However, it would be helpful to discuss this with your healthcare professional first if you consider using such natural medicines. 

If your healthcare provider agrees that it is okay to take such herbal supplements in conjunction with your prescription antidepressants, you can do so. Also, again make sure that you follow their instructions and those provided on the bottle to the letter. 

Make sure that you note any adverse effects while taking these natural medicines, like an upset stomach, a rapid heartbeat, or notice your blood pressure fluctuating. If you see such adverse effects occurring, stop taking the natural medicines immediately. 

Please let us know what you think of this article by leaving your comment below. 

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